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Table 2 Characteristics of the included studies

From: Effect of chronic kidney disease on total knee arthroplasty outcomes: a meta-analysis of matched control studies

Study

Study Design

No. of Patients

CKD

Non-CKD

Mean Age (y)

Female Gender

(%)

Follow-Up

mean (range) (y)

Stage of CKD

Method to identify CKD

Outcome Measures

CKD non-CKD

McCleery 2010

MR

59,288

3916

55,372

NC

NC

58.9

NC

Stage 1–5, including dialysis and transplant

ICD

Infection, revision;

Miric 2013

MR

36,882

2686

34,196

73

67

62.4

2.1 (0–5)

Stage 3 (69 %), stage 4 (3 %), stage 5 (5.5 %), unspecified stage (22 %), including transplant

ICD

Infection, revision, PE, DVT, mortality, re-admission;

Ponnusamy 2015

MR

4,182,887

1683

4,181,204

66.7

66.8

63.8

NC

Stage 5, with dialysis

ICD

Infection, mortality, transfusion;

Lizaur-Utrilla 2016

MR

45

15

30

69.3

70.1

53.3

3.4 (2–6)

Stage 5, including dialysis and transplant

Using diagnostic and surgical codes on the departmental arthroplasty database

Infection, transfusion;

Kuo 2016

MR

615

205

410

72.1

71.0

27.3

2.7 (2-4.8)

Stage 2–5 (eGFR < 60 mL/min/1.73 m2)

Calculating eGFR

LOS, transfusion;

Kuo 2017

MR

13,844

1459

12,385

71.6

70.3

76.8

2

Stage 1–5

ICD

Infection, PE, DVT, mortality, re-admission;

Bedard 2018

MR

35,894

4551

31,343

NC

NC

63.7

2

Stage 1–5

ICD

Revision;

  1. MR matched retrospective; CKD chronic kidney disease; NC not clear; LOS length of stay; PE pulmonary embolism; DVT deep vein thrombosis; ICD International Classification of Diseases; eGFR estimated glomerular filtration rate