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Table 2 Patient characteristics comparing those with and without acute kidney injury

From: Incidence and risk factors for acute kidney injury after total joint arthroplasty

 

No Acute Kidney Injury

Acute Kidney Injury

P Value

Demographic Characteristics

Age (years)

72.5 ± 10.0

71.1 ± 10.2

0.070

Sex (male:female)

317 (58.1%): 229 (41.9%)

146 (53.3%): 128 (46.7%)

0.193

Body Mass Index

31.8 ± 6.7

34.4 ± 7.4

<  0.001

Race/Ethnicity

 Non-Hispanic White

412 (75.5%)

171 (62.4%)

<  0.001

 Non-Hispanic Black

35 (6.41%)

39 (14.2%)

<  0.001

 Hispanic

16 (2.9%)

8 (2.9%)

0.993

 Asian

8 (1.5%)

3 (1.1%)

0.664

Comorbidities

 Tobacco smoking within 1 year

46 (8.4%)

30 (11.0%)

0.240

 Chronic steroid use

22 (4.0%)

10 (3.7%)

0.791

 Diabetes

113 (20.7%)

110 (40.2%)

<  0.001

 Hypertension

418 (76.6%)

241 (88.0%)

<  0.001

 COPD

28 (5.1%)

29 (10.6%)

0.004

 Congestive heart failure

6 (1.1%)

8 (2.9%)

0.058

 Bleeding disorders

27 (5.0%)

20 (7.3%)

0.171

 History of metastatic cancer

2 (0.4%)

1 (0.4%)

0.998

 Anemia

208 (38.1%)

145 (52.9%)

<  0.001

 Dyspnea

56 (10.3%)

47 (17.2%)

0.005

 Chronic kidney disease

76 (13.9%)

84 (30.7%)

<  0.001

Perioperative characteristics

 Primary osteoarthritis

524 (96.0%)

252 (92.0%)

0.017

 Total Hip Arthroplasty

198 (36.3%)

95 (34.7%)

0.654

 Total Knee Arthroplasty

348 (63.7%)

179 (65.3%)

0.654

 Bilateral procedure

5 (0.92%)

9 (3.28%)

0.014

 ASA Physical Classification

2.9 ± 0.5

3.0 ± 0.6

0.701

 Operative time (minutes)

91.3 ± 34.8

100.8 ± 42.2

0.001

 Sodium (mEq/L)

139.7 ± 2.9

139.4 ± 3.1

0.114

 BUN (mg/dL)

21.4 ± 10.3

27.2 ± 15.0

<  0.001

 Creatinine (mg/dL)

1.3 ± 1.5

1.5 ± 1.0

0.132

 Albumin (g/dL)

4.0 ± 0.4

3.9 ± 0.4

0.005

 Bilirubin (mg/dL)

0.6 ± 0.5

0.8 ± 1.2

0.205

 AST (units/L)

23.6 ± 1.08

23.2 ± 12.2

0.741

 ALP (units/L)

84.2 ± 33.4

91.2 ± 38.1

0.058

 WBC (×  109 cells/L)

7.5 ± 6.2

7.8 ± 3.3

0.377

 Hematocrit (%)

40.7 ± 4.7

38.5 ± 5.0

<  0.001

 Platelets (× 109 /L)

227.6 ± 60.3

232.4 ± 72.2

0.314

 PTT (sec)

29.8 ± 5.2

29.9 ± 5.5

0.913

 INR

1.1 ± 0.2

1.1 ± 0.3

0.538

 PT (sec)

12.5 ± 3.3

13.2 ± 4.9

0.568

  1. ALP Alkaline phosphatase, ASA American Society of Anesthesiologists, BUN Blood urea nitrogen, CHF Congestive heart failure, CKD Chronic kidney disease, COPD Chronic obstructive pulmonary disease, INR International normalized ratio, PTT Partial thromboplastin time, PT Prothrombin time, WBC White blood count