Defining a successful total knee arthroplasty: a systematic review of metrics of clinically important changes

Arthroplasty

Table 1 Study demographics arranged by design, PROM, change score, method of derivation, and follow-up

First author	Year	Study design	Total patients included^a	PROM(s)	Change score(s)	Method of calculation	Follow-up (year)
Berliner [11]	2017	3	562	KOOS, SF-12	MCID	Distribution	1
Blevins [12]	2019	3	228	KOOS, SF-12	MCID	Distribution	2
Busija [13]	2008	4	379 (105)	SF-36	MDC	Distribution	0.5, 1; 5
Chesworth [5]	2008	2	3,657 (1,578)	WOMAC	CID	Anchor	1
Clement [14]	2013	2	505	OKS, SF-12	MCID	Anchor	1
Clement [15]	2018	3	2,589	WOMAC	MCID, MDC, MIC	Both^b	1
Clement [16]	2019	3	2,589	SF-12	MCID, MDC, MIC	Both^b	1
Connelly [17]	2019	3	383; 301	KOOS, EQ-5D/VAS, NRS	PASS	Anchor	1; 3
Fontana [18]	2019	3	13,719 (6,480)	SF-36	MCID	Distribution	2
Goodman [19]	2020	3	10,622 (4,641)	KOOS	MCID	Anchor	2
Harris [20]	2021	2	637	KOOS	MCID	Anchor	1
Kagan [21]	2018	2	91	PROMIS	MCID	Distribution	0.13; 0.25; 0.5; 1
Kuo [22]	2020	2	1,088 (587)	KOOS	MCID	Both	1
Lawrie [23]	2020	3	172	PROMIS	MCID	Distribution	1
Lyman [24]	2018	3	4,953 (2,630)	KOOS	MCID, MDC, SCB	Both^c	2
Maxwell [25]	2013	2	271	WOMAC	PASS	Anchor	2.5; 5
Razak [26]	2016	3	3,328	OKS, SF-36	MCID	Distribution	5
Sayers [6]	2017	2	400 (190)	ICOAP	MCID, MID	Both^d	0.25; 0.5; 1

Study design: 1 = Randomized control trial, 2 = prospective cohort, 3 = retrospective cohort, 4 = case–control
MCID minimal clinically important difference, MDC minimum detectable change, CID clinically important difference, MIC minimal important change, PASS patient acceptable symptom state, SCB substantial clinical benefit. KOOS Knee Injury and Osteoarthritis Outcome Score, SF-12 Short Form-12, SF-36 Short Form-36, WOMAC Western Ontario McMaster University osteoarthritis index, OKS Oxford Knee Score, NRS Numeric Pain Rating Scale, PROMIS Patient-Reported Outcomes Measurement Information System, ICOAP Intermittent and Constant Osteoarthritis Pain questionnaire, EQ-5D-3L/VAS EuroQoL 5-dimension 3-level and visual analog scale
^aParenthesis indicates cohort of TKA patients specifically
^bMCID derived by anchor, MDC by distribution method, and MIC by anchor method
^cMCID derived by both methods, MDC by distribution, and SCB by anchor method
^dMCID derived by anchor, MID by distribution method

ISSN: 2524-7948