Table 4 Comparison of diagnostic efficiency between culture and mNGS
From: Value of mNGS in sonication fluid for the diagnosis of periprosthetic joint infection
Positive Diagnostic Test | No. of patients, (n = 37) | PJI (n = 24) | AF (n = 13) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|---|
Conventional Cultures | 37 | 16/8 | 0/13 | 66.67 | 100 | 100 | 61.9 | 66.67 |
Sonication fluid cultures | 37 | 17/7 | 1/12 | 70.83 | 92.31 | 94.44 | 63.16 | 63.14 |
Sonication fluid mNGS | 37 | 24/0 | 1/12 | 100 | 92.31 | 96 | 100 | 92.31 |