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Table 4 Comparison of diagnostic efficiency between culture and mNGS

From: Value of mNGS in sonication fluid for the diagnosis of periprosthetic joint infection

Positive Diagnostic Test No. of patients,
(n = 37)
PJI
(n = 24)
AF
(n = 13)
Sensitivity
(%)
Specificity
(%)
PPV
(%)
NPV
(%)
Accuracy
(%)
Conventional Cultures 37 16/8 0/13 66.67 100 100 61.9 66.67
Sonication fluid cultures 37 17/7 1/12 70.83 92.31 94.44 63.16 63.14
Sonication fluid mNGS 37 24/0 1/12 100 92.31 96 100 92.31
  1. PPV positive predictive rate, NPV negative predictive rate