Table 8 Associations of preoperative medical/psychological comorbidities with pain/opioid use after THA
From: Risk factors for pain after total hip arthroplasty: a systematic review
First author | Year | Study design | n | Follow-up | Outcome measures | Associations of preoperative comorbidities with postoperative pain/opioid use |
|---|---|---|---|---|---|---|
Prentice [9] | 2019 | RC | 12,560 | 1Â yr | Opioid usage | Higher postoperative opioid prescriptions with anxiety, chronic pulmonary disease, substance abuse, acquired immunodeficiency syndrome (AIDS), peripheral vascular disease, chronic blood loss anemia, congestive heart failure |
Bedard [11] | 2017 | RC | 37,393 | 1Â yr | Opioid use | Higher risk postoperative opioid use with preoperative anxiety, depression, drug use, alcohol use, smoking |
Brembo [12] | 2017 | PC | 223 | 3 mo | WOMAC | Worse pain with increased medical comorbidities |
Dowsey [15] | 2016 | PC | 382 | 1 and 2Â yr | HHS | Worse pain with poor mental function |
Greene [17] | 2016 | RC | 17,147 | 1Â yr | VAS for pain | Worse pain if using antidepressants |
Rajamaki [21] | 2015 | PC | 54 | 1–2 yr | NRS | Greater odds of pain in diabetes |
Lavernia [25] | 2014 | RC | 60 | 11 (3–24) mo | HHS | Worse pain in vitamin D insufficiency |
Petrovic [27] | 2014 | CC | 90 | 1 d | NRS | Higher odds of pain in type D personality, anxiety, depression |
Dowsey [22] | 2014 | PC | 835 | 1Â yr | HHS | Worse pain with increased medical comorbidities |
Pinto [32] | 2017 | CC | 48 | 4–6 mo | NRS | Worse pain with poor disease process perception and emotional representation |
Judge [2] | 2013 | PC | 1431 | 1–5 yr | OHS | Worse pain in medical comorbidities |
Singh [34] | 2013 | PC | 5707, 3289 | 2Â yr, 5Â yr | VAS for pain | No association |
Jones [35] | 2012 | PC | 231 | 3Â yr | WOMAC | Worse pain with cardiac disease |
Smith [37] | 2012 | PC | 1318 | 3Â yr | HHS | Worse pain with cardiac disease, hypertension, increase medical comorbidities, NSAID use |
Allen Butler [38] | 2011 | PR | 119 | 2Â yr | VAS, HHS, SF-12 | Worse pain with poor mental component score |
Singh [46] | 2010 | PC | 5707, 3289 | 2Â yr, 5Â yr | Pain medication use | Greater odds of pain, NSAID use, and opioid use in depression |
Riediger [44] | 2010 | PC | 79 | 8 wk | WOMAC, SF-36 | Worse pain in depression and somatoform disorders |
Rolfson [49] | 2009 | RC | 6158 | 1Â yr | VAS for pain | Worse pain in anxiety and depression |