Table 1 New scoring-based definition (2018)

Two positive cultures of the organism

Infected

Sinus tract with evidence of communication to the joint or visualization of the prosthesis

Preoperative diagnosis

Minor criteria

Score

Decision

Elevated CRP or D-Dimcr

2

≥6 Infected

2–5 Possibly infected^a

0–1 Not infected

Elevated ESR

1

Elevated synovial WBC or LE

3

Positive alpha-defensin

3

Elevated synovial PMN

2

Elevated synovial CRP

1

Intraoperative

Inconclusive pre-op score or dry tap

Score

Decision

Preoperative score

-

≥6 Infected

4–5 Inconclusive^b

≤3 Not infected

Positive histology

3

Positive purulence

3

Single positive culture

2