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Table 10 Comparison of the prior studies regarding Alpha defensin in the diagnosis of periprosthetic joint infection

From: Current relevance of biomarkers in diagnosis of periprosthetic joint infection: an update

Alpha defensin

Definition

Method

Sensitivity

Specificity

Sigmund et al., 2017 [47]

MSIS

Lateral Flow

69%

94%

Gehrke et al., 2018 [50]

MSIS

Lateral Flow

92.1%

100%

Riccio et al., 2018 [51]

MSIS

Lateral Flow

85%

97%

Kleiss et al., 2017 [52]

MSIS

ELISA

78%

97%

Bonanzinga et al., 2017 [53]

MSIS

ELISA

97%

97%