Table 6 Comparison of the prior studies regarding Interleukin 6 in the diagnosis of PJI
From: Current relevance of biomarkers in diagnosis of periprosthetic joint infection: an update
IL-6 | Infection definition | Cut-off (pg/mL) | Sensitivity | Specificity |
|---|---|---|---|---|
Bottner et al., JBJS Br, 2007 [23] | Based on findings of intraoperative culture and histology | 12 | 95% | 87% |
Glehr et al., CORR, 2013 [25] | MSIS 2011 | 2.55 | 94% | 53% |
Ettinger et al., CID, 2015 [27] | MSIS 2011 | 5.12 | 80% | 88% |
Klim et al., Int Orthop, 2020 [17] | MSIS 2011 | 5.7 | 77% | 70% |