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Table 5 A summary on the details of ML, strengths and limitations of the studies on diagnosis of PJI

From: Application of machine learning in the prevention of periprosthetic joint infection following total knee arthroplasty: a systematic review

First author [Ref.]

ML application

Algorithm

Statistical performance

Strengths

Limitations

Kuo, F.C. (2021) [8]

A personalized PJI diagnosis

Two-level stacked generalization architecture:

-Meta-classifier: Support vector machine;

-Base classifiers: Randomforest, eXtreme gradient boosting, logistic regression, naïve bayesian

AUC: 0.988. Accuracy: 96.4%. Recall: 0.981. F1 score: 0.97. Matthews correlation -coefficient: 0.926. Precision: 0.96

The performance outperformed that of International Consensus Meeting criteria; if-then rule was used for the explanation of the results

No external validation; small cohort size

Tao, Y. (2022) [13]

PJI pathological diagnosis

ResNet34 deep learning convolutional network

AUC: 0.8136. Average accuracy: 93.3%. Average recall rate: 0.9739. F1 score: 0.9482

External validation was conducted

Small cohort size

  1. AUC Area under the receiver operating characteristic curve, ML Machine learning, PJI Periprosthetic joint infection