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Table 1 Summary of all studies included in the systematic review

From: Functional somatic syndromes are associated with inferior outcomes and increased complications after hip and knee arthroplasty: a systematic review

Author, year

Country

Study design

No. of subjects

Surgery

Determination of FSS

Baseline FSS characteristics (n)

Outcome measures

Follow-up (mean)

Ayers, 2013 [43]

USA

prospective cohort

180

TKA

Oswestry questionnaire

Low back pain (89)

1) SF-36 physical functioning

6 months

Bedard, 2017 [26]

USA

retrospective cohort

37,393

THA

medical record

Myalgia (5,332); back pain (17,787)

1) postoperative opioid refills

1 year

Bedard, 2017 [27]

USA

retrospective cohort

73,959

TKA

medical record

Myalgia (10,137); back pain (27,705)

1) postoperative opioid refills

1 year

Bedard, 2018 [35]

USA

retrospective cohort

4,205

UKA

medical record

Myalgia (534); back pain (1,419)

1) postoperative opioid refills

1 year

Bican, 2011 [53]

USA

case control (matched)

118

TKA

medical record

Fibromyalgia (59)

1) postoperative satisfaction; 2) SF-36

3.4 years

Boyle, 2014 [36]

UK

retrospective cohort (matched)

345

TKA

medical record

Low back pain (40)

1) OKS; 2) American KSS; 3) SF-12

2 years

Brummett, 2013 [44]

USA

prospective cohort

519 (233 TKA, 286 THA)

TKA, THA

2011 ACR survey criteria

High FMSS (147); Moderate FMSS (199); Low FMSS (170)

1) postoperative opioid use

NA

Cancienne, 2018 [37]

USA

retrospective cohort

113,337

TKA

medical record

Fibromyalgia (24,920); back pain (69,908); migraines (7,753)

1) prolonged postoperative narcotic use

1 year

Clement, 2013 [45]

UK

prospective cohort

2,392

TKA

self-reported

Low back pain (829)

1) OKS; 2) SF-12; 3) patient satisfaction

1 year

Clement, 2018 [38]

UK

retrospective cohort

2,589

TKA

self-reported

Low back pain (1,309)

1) knee stiffness

1 year

Collados-Maestre, 2016 [46]

Spain

prospective cohort (matched)

144

TKA

medical record, self-reported

Low back pain (48)

1) SF-12; 2) WOMAC; 3) VAS for satisfaction; 4) KSS

min. of 2 years

Cregar, 2021 [39]

USA

retrospective cohort

106,874

TKA

medical record

Fibromyalgia (15,419)

1) LOA (1 year); 2) Revision (2 years)

min. of 2 years

D’Apuzzo, 2012 [40]

USA

retrospective cohort

110

TKA

medical record

Fibromyalgia (110)

1) American KSS; 2) Surgical complications; 3) Revision rate

7 years

Escobar, 2007 [47]

Spain

prospective cohort

640

TKA

self-reported from a questionnaire

Low back pain (411)

1) WOMAC; 2) SF-36

6 months

Hansen, 2017 [41]

Australia

retrospective cohort

15,020

TKA

medical record

Low back pain (349)

1) chronic opioid use

1 year

Inacio, 2016 [42]

Australia

retrospective cohort

9,525

THA

medical record

Migraines (28); back pain (1,367)

1) chronic opioid use

1 year

Kim, 2017 [28]

USA

retrospective cohort

57,545 (39,418 TKA, 18,127 THA)

TKA, THA

medical record

Fibromyaglia (4,719); back pain (23,478); migraines (4,546)

1) persistent opioid use

1 year

Loth, 2017 [29]

UK

retrospective cohort

251

THA

self-reported

Low back pain (135)

1) OHS; 2) FJS-12; 3) SF-12

1 year

Mehta, 2015 [48]

Canada

prospective cohort

494

TKA

self-reported (survey)

Low back pain (399)

1) Pain and Function/Daily Activity KOOS subscales

1 year

Moore, 2019 (a) [31]

USA

retrospective cohort (matched)

305,510

TKA

medical record

Fibromyalgia (152,755)

1) readmission rates; 2) total costs; 3) total reimbursements; 4) net losses for surgical and medical complications

90 days

Moore, 2019 (b) [30]

USA

retrospective cohort (matched)

305,510

TKA

medical record

Fibromyalgia (152,755)

1) Medical complications

90 days

Namba, 2018 [32]

USA

retrospective cohort

23,726

TKA

medical record

Fibromyalgia (381); back pain (2,754); migraines (332); chronic tension headaches (124)

1) number of postoperative opioid prescriptions

1 year

Prentice, 2019 [49]

USA

retrospective cohort

12,560

THA

medical record

Fibromyalgia (122); back pain (2,248); migraines (123); chronic tension headaches (54)

1) number of postoperative opioid prescriptions

1 year

Quintana, 2009 [50]

Spain

prospective cohort

788

THA

medical record

Back pain (402)

1) SF-36; 2) WOMAC

2 years

Sheth, 2020 [51]

USA

prospective cohort

258

TKA, THA

2011 ACR survey criteria, medical record

Fibromyalgia (8); back pain (61)

1) prolonged opioid use

90 days

Skrejborg, 2019 [33]

Denmark

consecutive cohort

352

TKA

medical record

Fibromyalgia (6)

1) NRS for pain

5 years

Sodhi, 2019 [34]

USA

retrospective cohort (matched)

305,510

TKA

medical record

Fibromyalgia (152,755)

1) Surgical complications

NA

Sullivan, 2009 [52]

Canada

prospective cohort

75

TKA

questionnaire, self-reported

Back pain (37)

1) WOMAC

6 weeks

  1. Abbreviations: THA Total hip arthroplasty, TKA Total knee arthroplasty, SF-36 36-Item Short Form Survey, iHOT-33 International Hip Outcomes Tool, HOS-ADL Hip Outcome Score Activities of Daily Living Subscale, OKS Oxford Knee Scores, KSS Knee Society Scores, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, BPI Brief Pain Inventory, LOA Lysis of adhesion, SANE Single Assessment Numeric Evaluation, VAS Visual Analogue Scale, FJS-12 Forgotten Joint Score-12, KOOS Knee Injury and Osteoarthritis Outcome Score, LEAS Lower extremity activity scale, NRS Numeric rating scale, TKA Total knee arthroplasty, THA Total hip arthroplasty ACR American College of Rheumatology, FMSS Fibromyalgia survey score