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Table 3 Pain scores over time and postoperative hospitalization metrics, stratified by treatment arm

From: A prospective, randomized trial of liposomal bupivacaine compared to conventional bupivacaine on pain control and postoperative opioid use in adults receiving adductor canal blocks for total knee arthroplasty

Variablea

Bupivacaine type used in adductor canal block (treatment arm)

 

Liposomal

Conventional

P-value

Pain scores over time

 PACU

  N

40

40

 

  Average pain score

0 [0–3.1]

0 [0–2.0]

0.94b

  Maximum pain score

0 [0–6.5]

0 [0–4.0]

0.94b

 POD-0

  N

40

40

 

  Average pain score

3.2 [2.5–4.4]

3.9 [2.6–4.8]

0.36b

  Maximum pain score

6 [5–7]

7 [5.1–8]

0.25b

 POD-1

  N

36

35

 

  Average pain score

4.5 [3.0–5.7]

5 [3.6–6.0]

0.43b

  Maximum pain score

6.7 [4–7]

7 [5–7.5]

0.61b

 POD-2

  N

34

34

 

  Average pain score

4 [1.9–5.8]

4.2 [3.0–5.6]

0.54b

  Maximum pain score

4.5 [2–7]

5.5 [4–7]

0.27b

Postoperative hospitalization

 Total time in PACU (h)

1.7 ± 0.5

2.0 ± 0.7

0.14c

 Time, anesthesia start to discharge (h)

25 [7.3–28.9]

23.7 [21.5–27.1]

0.478b

  1. PACU post-anesthesia care unit, POD postoperative day
  2. aData shown as median [interquartile range] or as mean ± standard deviation
  3. bMann Whitney U test
  4. c t-test