Table 3 Unadjusted analyses assessing the association of pre-operative opioid use and 6-month adverse events and PROMs

Unadjusted Analysis

Non-opioid user

n  = 824

Opioid user

n  = 359

P  value

Total adverse events

38.8%

38.8%

1.00

Acute significant adverse events

5.7%

5.3%

0.88

Post-discharge significant adverse events

6.5%

7.1%

0.78

Total significant adverse events

12.3%

12.7%

0.95

Unadjusted Analysis

Non-opioid user

n  = 714

Opioid user

n  = 317

P Value

6-month Oxford Score

39.5 (7.8)

38.8 (8.9)

0.22

6-month EQ-VAS

77.1 (17.8)

71.9 (20.5)

< 0.001

6-month “Much Better”

81.1%

80.3%

0.83