Table 4 Adjusted analyses assessing the association of preoperative opioid use with 6-month adverse events, the proportion of “Much Better” on the global perceived improvement scale, Oxford and EQ-VAS scores

Adjusted Analysis

Opioid user (Odds Ratio (95CI))

P  value

AUC

Total adverse events

0.85 (0.61, 1.19)

0.35

0.63

Acute significant adverse events

1.05 (0.55, 1.96)

0.87

0.66

Total significant adverse events

0.94 (0.57, 1.50)

0.79

0.64

6-month “Much Better”

0.93 (0.61, 1.43)

0.73

0.64

Adjusted Analysis

Opioid user (MD (95CI))

P value

Adjusted R ²

6-month Oxford Score

-0.34 (-1.63, 0.95)

0.60

0.08

6-month EQ-VAS

-2.26 (-5.16, 0.61)

0.12

0.09