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Trends of obesity rates between primary total hip arthroplasty patients and the general population from 2013 to 2020
Arthroplasty volume 4, Article number: 38 (2022)
The prevalence of obesity in total hip arthroplasty (THA) patients has been studied in the past. However, there has not been direct comparison against obesity in the general population. This study compared yearly trends in BMI and obesity rates between patients who had undergone primary THA and those from the general patient population.
We retrospectively reviewed all patients over the age of 18 who underwent primary, elective THA and those who had an annual routine physical exam between January 2013 and December 2020 at our academic tertiary medical center. Baseline demographics were controlled in our statistical models. Significance of yearly trends was determined through a linear regression analysis. Independent samples t-test and Chi-square test were used to compare means and proportions between the two groups, respectively.
A total of 11,250 primary THA patients and 1,039,918 annual physical exam patients were included. Average BMI for the THA group was significantly higher (P < 0.001) each year compared to the annual physicals group (APG). Higher obesity rates were observed in all obesity subgroups (all classes, and class I–III individually) for THA patients each year compared to the APG. Interestingly, while we found a significantly increasing trend in obesity for the general population (P < 0.001), BMI and obesity rates remained stable in the THA population.
While our general patient population showed significant increase in BMI and obesity over time, THA patients had higher, yet stable, BMI. Further investigation is required to determine the role of risk optimization in these findings.
Level III Evidence
Retrospective Cohort Study.
Obesity, defined as a body mass index (BMI) ≥ 30 kg/m2, is endemic in the United States (U.S) as its prevalence rate increased from 30.5% in 1999 to 42.4% in 2018 [1, 2]. Moreover, obesity is a risk factor for severe hip osteoarthritis, possibly contributing to the rise in demand for total hip arthroplasty (THA) [3, 4]. One study reported that compared with a general patient population, patients with obesity had 3.42 times, 5.24 times, and 8.56 times higher risk of undergoing THA for obesity class I, II, and III, respectively . The risk of complications such as infection, dislocations, and reoperations following THA is also higher in patients with obesity .
To understand the magnitude of its impact, researchers have evaluated trends in obesity rates for the total hip arthroplasty (THA) population at the national level using Nationwide Inpatient Sample (NIS) and the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) [1, 5, 6]. Studies since 1993 have all found increases in prevalence of obesity in THA patients over time [1, 5, 6]. Pirruccio et al.  also reported BMI in THA patients from 2008–2016 to be significantly higher when compared to the overall U.S adult population. Furthermore, Singh et al.  analyzed trends from 1993–2005 at their institution and found similar results: BMI and obesity rates in THA patients increased significantly over this period.
Despite these results, the advent of value-based payments in 2013 with emphasis on medical optimization and weight assessment may have influenced both patient selection and weight optimization for THA patients. Therefore, it is important to continue to track how obesity rates in the THA population compare to those of the general patient population not receiving THA. Evaluating the current trends over time enables surgeons to better understand the relationship between weight and arthritis progression, and whether optimization of THA patients requires additional focus on weight management. This study analyzed the trends in BMI and obesity rates in patients who had undergone primary THA at a large urban center against the general population of patients at the same institution. Our aim was to provide THA surgeons with the most recent information on obesity trends in order for them to internally assess the impact of current preoperative optimization strategies on patient BMI. Furthermore, our data may assist with shaping institutional guidelines for patients with obesity who may be candidates for THA. Subsequently, our results will provide better guidance for surgical teams to minimize risk following THA.
Materials and methods
We retrospectively analyzed patient data from a single, academic, orthopedic specialty hospital. The study population from our institution was stratified into two cohorts: (1) those who underwent elective primary THA between January 2013 and December 2020 and (2) all patients who had an annual routine physical exam and had not undergone a primary THA within the same period. Annual physical exams were identified using the Current Procedural Terminology (CPT) codes 99385, 99386, 99387, 99395, 99396, and 99397. Patients under 18 and those who underwent non-elective surgery such as revision THA or primary THA for hip fracture were excluded from this analysis. Approval from our Institutional Review Board (IRB) was obtained prior to conducting this study.
We collected baseline demographic variables which included age, sex, and BMI. All data were extracted using our institution's electronic medical records database (Epic Caboodle, version 15; Verona, WI, USA) and were de-identified and encrypted with Microsoft Excel software. The primary outcomes were average BMI and yearly trends between patients undergoing primary THA and those who had routine physical exams. We then separated the study population into five categories based on the CDC classification of obesity : underweight (BMI: < 18.5 kg/m2), all obese (BMI: ≥ 30 kg/m2), Class I obesity (BMI: 30–34.9 kg/m2), Class II obesity (BMI: 35–39.9 kg/m2), and Class III obesity (BMI: ≥ 40 kg/m2). The secondary outcome was the yearly trends in obesity rate between the two cohorts in each sub-group. Finally, we grouped study patients into matched age subgroups and compared average BMI between the two populations within each range. There was no funding source for the study.
Statistical analyses were performed using SPSS v25 (IBM Corporation, Armonk, New York, USA). Baseline characteristics such as age and gender were first compared using multilinear regression to ensure that these factors were statistically equivalent between the two cohorts. Pearson’s Chi-square (χ2) tests were utilized to detect statistical differences in categorical variables while independent sample two-sided t-tests were used for continuous variables. Furthermore, additional descriptive statistics were presented as means ± standard deviation for BMI and total counts (%) for obesity rates. A linear regression was used to calculate the difference in means for BMI and the unstandardized beta values. Linear regression with Pearson’s correlation coefficient (r) was used to determine the significance of the yearly trends for both groups. A significant slope (Pearson’s r) indicated an increasing or decreasing trend, while a lack of significance indicated a stable trend. A P-value of less than 0.05 was set as statistically significant.
This study included 11,250 primary THA patients and 1,039,918 annual physical exam (APG) patients. Comparison of baseline characteristics between the two groups found differences in age and gender; patients in the primary THA group were older (63.08 years ± 11.56 years vs. 44.17 years ± 14.99 years, P < 0.001) and had higher percentage of males (43.0% vs. 33.5%, P < 0.001) than the APG group (Table 1).
After adjusting for demographics, there were significant differences in average BMI between groups each year. Mean BMI for the THA group was significantly greater (P < 0.001) each year compared to the APG (Table 2).
Furthermore, BMI trends analysis showed a significant positive slope (P < 0.001) for the APG, indicating an increasing BMI trend for our general population (Fig. 1, Table 3). Conversely, the slope of the THA group was not significant and was essentially flat. This indicated that BMI had been stable over this time of period for our THA patients (Fig. 1, Table 3).
After stratification into BMI categories, significant differences in the proportion of patients from each category were found each year between cohorts (P < 0.01). The proportion of underweight THA patients was significantly lower every year except 2018 and 2019, compared to the APG (Table 4). In contrast, the proportion of patients in the remaining four subdivisions was significantly higher for the THA group each year compared to the APG (Table 4).
Trend analysis of obesity rates for the five categories exhibited significance in all slopes for the APG (P < 0.001) and no significance for the THA group (Table 3). For the underweight category, there was a significant negative slope for the APG, but no significance was found for the THA group. This indicated progressively lower percentage of underweight patients in the APG over time, but no change for those undergoing THA (Figs. 2 and 3). In the obese, Class I, Class II, and Class III subdivisions, significant positive slopes, indicating progressively higher rate of obesity, were found for the APG, but not for THA patients (Figs. 2 and 3).
On analysis of matched age subgroups, we once again found significant differences in average BMI. Mean BMI for the THA group was significantly greater (P < 0.001) for each age range compared to the APG (Table 5), which was similar to our non-matched results.
Obesity continues to be more prevalent in the United States, which contributes to the risk of developing osteoarthritis that leads to an increased demand for THA. Obesity rates are also steadily increasing, and, by 2030, are expected to exceed 50% . Previous literature has shown an increase in obesity rates over time for patients undergoing THA, and that THA patients have a significantly higher average BMI compared to the overall United States population . Additionally, patients with obesity may require THA at a younger age and are at a higher risk for perioperative complications after THA, including infection, wound complications, and aseptic loosening, which are more profound for THA vs. TKA [10,11,12,13]. Despite lower objective outcomes, obese patients are shown to benefit significantly from THA, as large studies demonstrated significant improvement after THA for all weight classes [14, 15]. Thus, more evidence is needed to evaluate protocols around THA in patients with obesity. The introduction of value-based payments in the most recent decade has shown an increased focus on such protocols like weight optimization and weight assessment for THA patients. Therefore, the goal of this study was to investigate change in obesity rates from 2013–2020 for patients receiving THA at a large urban academic health system relative to a population receiving annual physicals at the same institution. Our findings suggest that while THA patients are significantly more obese than the general population of patients, there have been stable trends in BMI and obesity rates over time among these patients compared to increasing trends seen in our general population.
Prior research has shown increasing prevalence of obesity in the United States, and that those who receive THA have higher BMI than the average American [5, 9]. Our findings corroborated this finding. Average BMI for the general patient population at our institution has steadily increased over the last decade. Those who received THA had higher average BMI than the APG group in every year studied. However, while prior studies have shown increase, over time, of average BMI for THA patients , our analysis showed that in the last eight years, there has been no significant positive or negative trend in obesity rates for our patients who undergo THA. In 2013, our institution was one of the first to enter into a value-based care contract through BPCI. These programs penalize institutions for poor outcomes and encourage preoperative optimization of modifiable risk factors like obesity. While there is substantial evidence for increased complications and worse outcomes for THA in patients with morbid obesity, studies have also shown that these patients benefit significantly from THA [17,18,19]. In this study period, our THA patients did not show the upward trend in prevalence of obesity demonstrated by historical data and our own general patient population over the same period. Although the average BMI among our THA was greater than the APG cohort at all-time points. Further study of the effects of optimization and future direction for THA in patients with obesity may be warranted.
A more granular analysis separating patients in to underweight, normal weight, Class I obesity, Class II obesity, and Class III obesity found proportion of THA patients in all five weight classes was stable during the study period. Conversely, the APG cohort had progressively higher proportions of patients in all obese classifications, and lower proportions of patients in the underweight category. Previous literature has shown that Class III obese THA patients have longer LOS and higher readmission and major complication rates than patients without obesity [20, 21]. A study by Fu et al. investigating THA in patients with obesity found that malnutrition is more prevalent in patients with Class III obesity than in Class I obesity, and portends worse outcomes than obesity itself . Katakam et al. analyzed 1256 THAs and found that obesity Class III patients were 2.5 times more likely not to achieve minimal clinically relevant improvement in patient-reported outcome measures after surgery . As a result, hospitals and surgeons will need to enhance optimization and patient selection for THA.
While previous literature has clearly linked obesity to worse outcomes and increased risk of complications after THA, there is less consensus regarding outcomes for underweight THA patients. Studies have shown that underweight patients who undergo primary THA require longer LOS and are readmitted more often than patients in normal weight categories, but they do not have higher rates of complications [24,25,26]. Possible explanations for these findings include prevalence of malnutrition among underweight patients . Studies have also shown a relatively low rate of THA in patients who are underweight . Our findings concurred with this result, as underweight patients were the only weight category studied where proportions were consistently lower for the THA cohort than for the APG cohort over the study period.
As a retrospective study extracted from electronic medical records, our data are limited, depending on accurate documentation such as ICD coding of physical exams and THA. Additionally, specifically selecting patients who have received an annual physical exam at our healthcare network to represent the general public may be biased towards those with more health access or may not account for those seeking care for a wide range of reasons, which could have influenced the lower obesity rates observed in our APG. The generalizability of our data is further limited due to the regional differences in obesity trends observed as the levels of obesity in our metropolitan urban area may differ from other areas of the country with higher or lower levels. Finally, the BMI of the general public may not be reflected in patients who self-select to undergo annual physical examinations. Despite these limitations, our observational study used sound design and statistical methodology, which, combined with access to a comprehensive patient record database, allows us to be confident in the reliability and validity of our data.
Our study showed higher average BMI every year for THA patients vs. APG patients. However, contrary to prior studies, while BMI and obesity rates in each class for APG patients increased significantly over the eight-year period, there was no such trend among patients who received THA. This suggests that while our general patient population became increasingly obese, obesity rates among our THA patients since 2013 have remained flat. With access to this information, surgeons performing THA can consider if additional counseling for weight management is necessary, or if focus on optimization of other conditions is warranted prior to surgery. Furthermore, our data can inform institutional THA eligibility criteria for patients with obesity. Further research on the effect of value-based payment-driven optimization and patient selection efforts in THA is necessary.
Availability of data and materials
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
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No funding was provided for this study.
Ethics approval and consent to participate
The present study was approved by our institutional review board (IRB). Consent to participate is not applicable.
Consent for publication
Consent to publish was obtained from all individual participants included in the study.
N.M, T.C, V.S, C.S.S, and J.C.R have nothing to disclose. R.S owns stock or stock options in Intellijoint, Gauss Surgical, and PSI. R.S is also a paid consultant for Smith & Nephew and Intellijoint. C.M.L is an unpaid consultant for FundamentalVR.
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Muthusamy, N., Christensen, T., Singh, V. et al. Trends of obesity rates between primary total hip arthroplasty patients and the general population from 2013 to 2020. Arthroplasty 4, 38 (2022). https://doi.org/10.1186/s42836-022-00140-9
- Body mass index (BMI)
- Total hip arthroplasty
- Annual physicals